Rizatriptan impurity 20 Oxalate CAS 144035-23-4 (free base)
| CAS No. | 144035-23-4 (free base) |
| Molecular Formula | C13H15N5 |
| Molecular Weight | N/A |
| Category | Pharmacopoeial Impurity Standards / EP Impurities |
| Availability | In Stock |
Chemical Structure
Description
Recommended for quantitative analysis by HPLC, GC, LC-MS/MS, or GC-MS as an external calibration standard; it can also be used for spiked-recovery experiments, LOD/LOQ determination, and LC-MS/MS multiple-reaction-monitoring (MRM) calibration.
As a process- or degradation-related impurity, Rizatriptan impurity 20 Oxalate (CAS 144035-23-4 (free base), C13H15N5C2H2O4) is essential for impurity profiling, related-substances testing, and forced-degradation studies in pharmaceutical development.
Based on its molecular formula C13H15N5C2H2O4, Rizatriptan impurity 20 Oxalate contains a flavonoid core, an amide group, a hydroxyl group, an ether linkage; these features give the compound characteristic absorption bands in UV spectroscopy. The molecular weight of 331.33 g/mol is directly relevant to the identification of the molecular ion in mass spectrometry. Nitrogen-containing functional groups confer excellent ionization efficiency in positive-ion electrospray (ESI) mode, making the compound well suited to LC-MS/MS analysis.
The assigned purity is verified by mass-balance and quantitative NMR (qNMR) approaches, with the expanded uncertainty reported at a 95% confidence level (k=2). Batch homogeneity and stability are independently assessed for every lot.
Physical & Chemical Properties
| Molecular Formula | C13H15N5 C2H2O4 |
| Molecular Weight | 331.33 g/mol |
| Appearance | Pale yellow to yellow crystalline powder |
| Purity | 97%+ |
| Storage | Store at 2-8°C, protect from light, keep sealed and dry |
| Solubility (reference) | Soluble in DMSO, DMF, methanol |
| Stability | May oxidize slowly on prolonged air exposure; Light-sensitive; avoid direct strong light; Hygroscopic; reseal immediately after opening |
| Degree of Unsaturation (DBE) | 10.0 |
| UV Absorption | UV-absorbing |
| Structural Features | Aromatic ring present |
| Nitrogen Atoms | 5 |
Related Rizatriptan Standards
- Rizatriptan EP Impurity G (CAS 1000673-59-5)
- Rizatriptan Dimer Impurity 3 (CAS 1016900-25-6)
- Rizatriptan impurity 01 (CAS 1030849-63-8)
- Rizatriptan Impurity N8 (CAS 1034806-43-3)
- Rizatriptan Impurity 14 (CAS 110-95-2)
- Rizatriptan Impurity 4 (CAS 1135479-41-2)
- Rizatriptan Dimer (CAS 1135479-44-5)
- Rizatriptan Impurity 15 (CAS 114094-45-0)
Recommended Standards
- Cefuroxime Impurity 21 (CAS CATO-C4X-124521)
- Granisetron EP Impurity H (CAS 4498-67-3)
- Dabigatran Impurity 75 (CAS 355809-32-4)
- 4-(Aminomethyl)-2,5-dimethylfuran-3-carboxylic acid (CAS 524052-51-5)
- 3-(2-Chlorothiophen-3-yl)-5-methylisoxazole-4-carboxylic acid (CAS 14483-57-9)
- 3-(trifluoromethyl)-5H,6H,7H,8H-imidazo[1,5-a]pyridine-1-carboxylic acid (CAS 1780407-08-0)
- 1-(1-(1H-Benzo[d]imidazol-2-yl)-2-phenylethyl)-3-(3-cyanophenyl)urea (CAS 1197844-28-2)
- Methyl 2-(4-bromo-2-cyano-5-(difluoromethyl)phenyl)acetate (CAS 1805519-23-6)
- Tert-butyl 4-((5-bromopyrimidin-2-yl)oxy)piperidine-1-carboxylate (CAS 832735-41-8)
- Insulin Degludec Impurity 3 (CAS CATO-C4X-21573)
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